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Ativan (Lorazepam) belongs to a group of drugs called benzodiazepines. Lorazepam affects chemicals in the brain that may be unbalanced in people with anxiety. Benzodiazepines affect gamma-aminobutyric acid (GABA), a neurotransmitter chemical that nerves in the brain use to send messages to one another. By influencing GABA, benzodiazepines reduce the activity of nerves in the brain.
Ativan for anxiety
Ativan is indicated for treating:
• Anxiety disorders
• Panic attacks.
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• Before taking lorazepam, tell your doctor or pharmacist if you are allergic to it; or to other benzodiazepines.
• Do not use Ativan if you have: kidney or liver disease, breathing problems, mental disorders, alcohol addiction.
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Usual Geriatric Dose for Anxiety:
Older or debilitated patients:
-Initial dose: 1 to 2 mg orally per day, given in divided doses
-The dosage should be increased gradually when needed to help avoid adverse effects.
-The daily dosage may vary from 1 to 10 mg/day.
-When higher dosage is indicated, the evening dose should be increased before the daytime doses.
-Use of anxiolytic agents is typically not needed to treat anxiety/tension associated with the stress of everyday life.
-Clinical studies have not evaluated this drug for efficacy in long-term treatment (e.g., greater than 4 months).
-Management of anxiety disorders
-Short-term relief of the symptoms of anxiety or anxiety associated with depressive symptoms
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Take the medicine as soon as you can, but skip the missed dose if it is almost time for your next dose. Do not take two doses at one time.
What happens if I overdose?
Seek emergency medical attention or call the Poison Help line at 1-800-222-1222. An overdose of lorazepam can be fatal if you take it with alcohol, opioid medicine, or other drugs that cause drowsiness or slow your breathing.
Overdose symptoms may include extreme drowsiness, confusion, slurred speech, feeling restless, muscle weakness, loss of balance or coordination, feeling light-headed, slow heartbeats, weak or shallow breathing, or coma.
What should I avoid while taking Ativan?
Avoid drinking alcohol. Dangerous side effects or death could occur.
Avoid driving or hazardous activity until you know how this medicine will affect you. Dizziness or drowsiness can cause falls, accidents, or severe injuries.
Ativan side effects
Get emergency medical help if you have signs of an allergic reaction to Ativan: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.
Ativan can slow or stop your breathing, especially if you have recently used an opioid medication, alcohol, or other drugs that can slow your breathing. A person caring for you should seek emergency medical attention if you have weak or shallow breathing, if you are hard to wake up, or if you stop breathing.
Call your doctor at once if you have:
- severe drowsiness;
- unusual changes in mood or behavior;
- sudden restless feeling or excitement;
- thoughts of suicide or hurting yourself;
- confusion, aggression, hallucinations;
- sleep problems;
- vision changes; or
- dark urine, or jaundice (yellowing of the skin or eyes).
Common Ativan side effects may include:
- dizziness, drowsiness;
- weakness; or
- feeling unsteady.
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
What other drugs will affect Ativan?
Taking Ativan with other drugs that make you sleepy or slow your breathing can cause dangerous side effects or death. Ask your doctor before using opioid medication, a sleeping pill, a muscle relaxer, prescription cough medicine, or medicine for depression or seizures.
Tell your doctor about all your other medicines, especially:
- probenecid, aminophylline, or theophylline;
- any other medicines to treat anxiety;
- medicine to treat mental illness;
- seizure medicine; or
- medicine that contains an antihistamine (such as sleep medicine, cold or allergy medicine).
This list is not complete. Other drugs may interact with lorazepam, including prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible drug interactions are listed here.